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    BPH is not cancer; it is a condition that affects a man's prostate, a gland found between the bladder and the urethra. As a man ages, the prostate gland slowly grows bigger (or enlarges) and may press on the urethra and cause the flow of urine to be slower and less forceful. BPH is characterized by urinary frequency, urgency, passing urine more often (particularly at night), weakened stream and incomplete bladder emptying. Such symptoms can have significant negative impact in quality of life, leading many men to seek treatment, said Pisco. We need innovative technologies, such as prostatic artery embolization, to continue to improve outcomes and minimize patient discomfort and morbidity when managing enlarged prostates, he added.

    An estimated 19 million men in this country have symptomatic BPH, (14 million undiagnosed; 2 million diagnosed adult sex toys but untreated). Statistics show that a small amount of prostate enlargement is present in many men over age 40, as many as 50 percent experience symptoms of an enlarged prostate by age 60 and more than 90 percent of men over the age of 85 will report symptoms.

    The men who were treated with prostatic artery embolization showed significant clinical improvement, said Pisco. In this study, 84 men (ranging in ages from 52 to 85) with symptomatic BPH underwent prostatic artery embolization after failing other medical treatments for at least six months, said Pisco. The men were followed for more than nine months (on average), and PAE was found to be technically successful in 98.5 percent of the patients -- with 77 men showing excellent improvement, six men slight improvement (but needing no medications) and one experiencing no improvement (due to receiving an incomplete embolization), he added. Two hours after PAE, most men were passing urine less frequently. It was impossible to embolize both prostate arteries in.

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    Screening HIV-infected patients for hepatitis C only once upon entry into HIV care is not sufficient, according to study author Lynn E. Taylor, MD, of Brown University in Providence, R. I. The standard of care needs to change. HIV-infected persons should have access to ongoing screening for hepatitis C. Doctors and patients may not be aware of or freely discuss all risk behaviors that may lead to hepatitis C infection. These behaviors are often stigmatized. Patients may not feel comfortable discussing these risk factors nor may they be aware of all the ways in which hepatitis C may be transmitted via blood.


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    Those infected at birth were four times more likely to choose to terminate the pregnancy -- 41 percent of them did so -- compared with those who contracted HIV later in life, 10 percent of whom ended the pregnancy.

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    Funding for the study came from the National Institutes of Health and the Doris Duke Charitable Foundation.

    Conflict-of-interest disclosure: Kelly Gebo has received research funding from Tibotec, developer of anti-infective pharmaceuticals, including HIV/AIDS drugs. The terms of these arrangements are being managed by The Johns Hopkins University in accordance with its conflict-of-interest policies.

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    s, the vaccine also effectively prevented HPV-persistent infection in 86 percent of the participants without previous exposure.

    This is the first study to show that this vaccine works in boys, Giuliano said. As long as we have a poor record of vaccinations in girls, boys should also be vaccinated.

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    The international trial included physicians and patients in four U.S. medical centers, as well as in Australia, Brazil, Canada, Germany, Mexico, Norway, Peru and Taiwan.

    The project was supported by grants from both public and private sources. The trial was designed by the sponsor, Merck & Co, Inc., in collaboration with external investigators and an external data and safety monitoring board.


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